Saturday, March 30, 2013

Kenyan separatists deny being behind deadly resort attack

By Joseph Akwiri

MOMBASA, Kenya (Reuters) - A Kenyan separatist movement denied on Friday accusations by the authorities that it was behind a raid in a coastal resort that killed eight people, although it said former members may have been involved.

Armed police officers shot dead six attackers and two policemen were killed in Thursday's early morning raid on a casino popular with tourists in Malindi. Officials blamed the banned Mombasa Republican Council (MRC).

A series of attacks blamed on the movement have damaged prospects for growth and investment along Kenya's coast, a major tourist draw, and in Mombasa, an economically vital port city.

"Police should stop using the MRC as a scapegoat for failing to protect Kenyans," senior MRC member Omar Bebo told Reuters. He said that criminal gangs "have taken advantage of our sour relationship with government to cause trouble".

"Some of these gangs are formed by splinter groups of youths who decamped from the MRC because we rejected their call to engage in violence. Those are the people police should be chasing," he said by telephone.

The MRC feeds off local discontent largely based on long-held grievances over land and frustration at the perceived economic marginalization of the coast by the central government.

Police suspected the group targeted the Italian-owned casino in order to steal cash to fund their activities. Four suspects were arrested and dozens of others fled.

"We know we have some youth who decided to ignore our call for peace, and might also be involved in these attacks, but we told them they are on their own," Omar said. "MRC is not responsible for their actions, and we have disowned them."

On Thursday night police increased security around a police station in Kilifi, west of Mombasa, another MRC stronghold, saying they received reports that MRC youths planned a raid.

Beatrice Gachago, area police chief, told Reuters that she had ordered more night patrols after receiving the intelligence reports. "We are not taking anything for granted," she said.

(Writing by Edmund Blair; Editing by Louise Ireland)

Source: http://news.yahoo.com/kenyan-separatists-deny-behind-deadly-resort-attack-115155534.html

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Friday, March 29, 2013

Putin flexes Russian military muscle in naval exercise

By Alexei Anishchuk

MOSCOW (Reuters) - President Vladimir Putin ordered large-scale military exercises in the Black Sea on Thursday, projecting Russian power towards Europe and the Middle East in a move that may vex neighbors.

Officials suggested the surprise drill would test reaction speed and combat readiness, but Putin's order also seemed a signal to the West of Russia's presence in the region.

Presidential spokesman Dmitry Peskov told reporters Putin triggered the maneuvers as he flew back overnight from South Africa after a summit of the BRICS emerging economies.

Peskov said 36 warships and an unspecified number of planes would take part, but not how long exercises would last.

Putin has stressed the importance of a strong and agile military since returning to the presidency last May. In 13 years in power, he has often cited external threats when talking of the need for reliable armed forces and Russian political unity.

Late last month, Putin ordered military leaders to make urgent improvements to the armed forces in the next few years, saying Russia must thwart Western attempts to tip the balance of power. He said maneuvers must be held with less advance warning, to keep soldiers on their toes.

Putin, 60, has used his role as commander-in-chief to cast himself as a strong leader for whom national security is foremost. State media emphasized he ordered the exercises from a plane in the dead of night.

Russia's Black Sea Fleet, whose main base is in the Ukrainian port of Sevastopol, was instrumental in a war with ex-Soviet neighbor Georgia in 2008 over the Russian-backed breakaway regions of South Ossetia and Abkhazia.

In addition to Georgia and Ukraine, Russia shares the Black Sea with Turkey, Bulgaria and Romania.

But Russian foreign affairs analyst Fyodor Lukyanov said the exercises were "more likely part of a wider attempt to reconfirm that Russia's navy and military forces in the south are still able to play a political and geopolitical role."

"It is flexing muscles and may have more to do with what is happening in the Mediterranean, around Syria, than in the Black Sea," said Lukyanov, editor of journal Russia in Global Affairs.

REGIONAL ROLE

Russia's modest naval maintenance and supply facility in Syria is its only military base outside the former Soviet Union, and the Defense Ministry recently announced plans to deploy a naval unit in the Mediterranean on a permanent basis.

Russia has clashed diplomatically with the West throughout a two-year conflict that has killed more than 70,000 people in Syria, using its U.N. Security Council veto to block Western efforts to push President Bashar al-Assad from power.

Moscow-based military analyst Alexander Golts said unannounced exercises are good for Russia's military, but the location could raise questions among Russia's neighbors.

"We will be watching these exercises very closely as Georgia has its own experience with Russia," Tedo Japaridze, head of the Georgian parliament's foreign relations committee, told Reuters. He said all Black Sea nations have the right to hold exercises.

The Kremlin portrays Georgian President Mikheil Saakashvili as a bellicose leader, and Russia said last week annual U.S.-Georgian training exercises that began this month in Georgia, far from the Black Sea coast, put peace at risk.

Meanwhile, disputes with Ukraine over Moscow's continued lease of the Black Sea navy base have been a thorn in relations with its former Soviet neighbor.

Peskov said the number of servicemen participating was short of the threshold requiring Russia to notify other nations of its plans, but Russian news agency Itar-Tass quoted a spokesman for Ukraine's foreign minister, who was in Moscow on Thursday, as saying Ukraine had been informed in advance.

A NATO official said the Western alliance was not given notice and that "exercises are part of what the military do. NATO also conducts regular military exercises, which are not directed at anyone". But he said NATO would like to see greater openness from Russia, including on military exercises.

(Additional reporting by Gabriela Baczynska in Moscow, Pavel Polityuk in Kiev, Margarita Antidze in Tbilisi and Adrian Croft in Brussels; Writing by Alissa de Carbonnel and Steve Gutterman; Editing by Jason Webb)

Source: http://news.yahoo.com/putin-flexes-russias-military-muscle-black-sea-exercises-150222901.html

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Learning to Let Go (for the Health of Your Company) | MSPmentor

I?m a control freak. But I?m trying to break the habit. The latest example: I?m no longer running the underlying IT platforms that drive MSPmentor?s two sister sites: The VAR Guy and Talkin? Cloud. Soon, I will let go of MSPmentor?s underlying technology as well. What does this journey mean? Before you jump to conclusions, here are some important lessons for MSP entrepreneurs who are growing their businesses, considering potential M&A strategies, and struggling to delegate daily tasks.

First, some background: I?ve been an accidental CIO for about five years now. When we launched Nine Lives Media (MSPmentor?s parent) in January 2008, I had some basic IT skills and some hunches about how online media would evolve. Similarly, co-founder Amy Katz had some great business development and sales experience to help her build financial models for our business. Amy quickly took on the CEO role and I took on the editorial director role ? but there was that sort-of CIO responsibility that came along with it.

Fortunately, we had a great web design and architecture partner. And we found the right platforms (WordPress, MySQL, Rackspace, etc.) for the start of our IT journey. But somewhere around year three of our our business (2010-2011), I knew I would eventually need to hand off my technical responsibilities. As the old saying goes: Hire the best person for the job. And when it comes to CIO-type functions, I was good for a Stage 1 company. That?s it.

Stage 2 and Beyond

Enter Penton Media. I think Amy and the Penton management team started talking M&A around Q2 of 2011. Amy always kept me looped in on the discussions. But ultimately she negotiated the deal. Among the big potential perks I hoped to achieve: Instead of trying to build a robust, scalable content management platform of our own, I hoped Penton would acquire us so that Nine Lives could ultimately run our web sites and media operations atop Penton?s web platform.

In other words: If you want to transform your house into a mansion it?s smart to plug into the existing city infrastructure rather than building your own power plant. That became a central part of the plan when Penton acquired Nine Lives Media in August 2011. But the complete IT transition wouldn?t happen overnight.

Our first step was migrating all the basic business operations ? email, finance, accounting, payroll, etc. ? to Penton?s systems. That occurred rapidly, and Amy made it all happen.

At the same time we watched how Penton began to standardize its own content management system on a single platform code-named PISCES. Look under the hood, and you?ll find that PISCES is built on Drupal, an open source CMS. One by one, Penton was moving its various media brands onto Drupal. We knew Nine Lives Media had to chart a similar course.

But there were plenty of inflection points. We had to get our editorial team trained on Drupal (special thanks to Charlene O?Hanlon for taking the lead on learning Drupal.) I think some peers at Penton wondered if I was ready to truly ?let go? of Nine Lives? content management system. We also had to sort out how our ad serving system would work on Penton?s IT infrastructure. Most of all: I wanted to see our sites running? ? even in a controlled environment ? on Penton?s PISCES platform before we pulled back the curtain on a very public migration.

Experts In the House

That?s where folks like Penton VP of Internet Technology Nino Tasca and Senior Project Manager Matt Tulloch enter the picture. Basically, PISCES is Tasca?s baby. And Tulloch is the migration expert who made sure The VAR Guy and Talkin? Cloud had safe passage to PISCES. Tulloch will repeat that feat sometime soon for MSPmentor (stay tuned).

Like any IT project, we encountered plenty of challenges amid our migration. But the bottom line is our sites and business continues to grow; I?m still blogging away; and Penton is now running two-thirds of our media platforms. The final one-third of the migration is within sight?

The Lesson for MSPs and Entrepreneurs

When you started your business, you likely did a little bit of everything because you had to. But as you consider potential business growth ? or maybe even an M&A deal ? down the road here?s what I?d do:

  • First, make a list of the key tasks you want/need to delegate over time.
  • Second, make a list of the skills that organic hiring or an M&A deal will bring to the table.

As an entrepreneur or business owner you need to do less ? not more. In some ways it?s fine to be a control freak. But when you?re no longer the smartest guy or gal in the room on a specific t0pic then its time to eat some humble pie, delegate fast and get back to what you love: The creative process of building a business, rather than the nuts and bolts of running a business.

As for me, I?m still doing what I love. But my job description no longer includes after-hours website support for The VAR Guy and Talkin? Cloud. That?s my opportunity to say goodnight.

Source: http://www.mspmentor.net/2013/03/28/learning-to-let-go-for-the-health-of-your-company/

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Thursday, March 28, 2013

Auto App Updater Automates Your App Store Updates

Auto App Updater Automates Your App Store UpdatesiOS (Jailbroken): It doesn't take all that many taps to go in and update your apps on your iPhone or iPad, but if you'd prefer it just happened automatically in the background, Auto App Updater is a jailbreak app that does just that.

With Auto App Updater installed you can pop into the Settings on your iOS device, and configure it to automatically install app updates for you at timed intervals. When it's set up, Auto App Updater runs in the background at set intervals to check for updates, and installs whatever is new. When it's done, it sends you a notification saying how many updates were installed. You can blacklist apps from updating if you're holding off because of a specific bug, and you can also dig into the update history to see what's new. Unfortunately, you can't set up a specific time for Auto App Updater to run, but you can restrict it to Wi-Fi only so you're not wasting any data. Auto updating your apps isn't always a good idea since occasionally an update breaks functionality, but if you're willing to risk it Auto App Updater works great.

Auto App Updater ($2.99) | Modmyi Repository via Modmyi

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/s_7bu0VAN5Q/auto-app-updater-automates-your-app-store-updates

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Court justices take on fertility question

Supreme Court Associate Justice Elena Kagan attends U.S. President Barack Obama's State??In Tuesday's oral arguments over whether California's ban on gay marriage is unconstitutional, a few of the liberal Supreme Court justices took aim at one of the central arguments made by gay marriage opponents: that the ability to naturally procreate is key to the definition of marriage.

Charles Cooper, the attorney representing proponents of California's Proposition 8 ban on gay marriage, argued that allowing same-sex nuptials would fundamentally change the definition of marriage for the worse.

"The concern is that redefining marriage as a genderless institution will sever its abiding connection to its historic traditional procreative purposes, and it will refocus the purpose of marriage and the definition of marriage away from the raising of children and to the emotional needs and desires of adults," Cooper said.

Justice Elena Kagan, an appointee of President Barack Obama, pressed Cooper on that argument, asking him why then the government could not bar couples who are both over the age of 55 from marrying, on the assumption that they are infertile.

Cooper replied that it would violate the Constitution to ban older people from marrying.

"Your Honor, even with respect to couples over the age of 55, it is very rare that both couples?both parties to the couple are infertile," Cooper began, before he was interrupted by the audience in the courtroom erupting into laughter.

"I can just assure you, if both the woman and the man are over the age of 55, there are not a lot of children coming out of that marriage," Kagan retorted, provoking more laughter.

Justice Antonin Scalia jumped into the fray, joking that "Strom Thurmond was not the chairman of the Senate committee when Justice Kagan was confirmed."

Thurmond, the late South Carolina Republican senator, fathered children well into his 70s with his decades-younger wife. Kagan pointed out that in her hypothetical, both members of the couple would be over 55, not just the man.

Justice Ruth Bader Ginsburg also cast doubt on the procreation aspect of Cooper's argument, reminding him that the Supreme Court has ruled in the past that prisoners have a right to marry even if they are locked up and unable to procreate with their new spouse. Cooper replied that even in that case, the prison was a co-ed facility and it's possible the prisoner would have had children.

Outside of this exchange, Cooper did not rely heavily on the natural procreation point in arguing the government should bar gay people from marrying. In his brief opening statement, Cooper urged the justices to allow Americans to engage in "an an earnest debate over whether the age-old definition of marriage should be changed to include same-sex couples" by not declaring from the bench that gay marriage bans are unconstitutional.

Source: http://news.yahoo.com/blogs/ticket/gay-marriage-case-justices-focus-trade-laughs-fertility-220612049--election.html

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Tuesday, March 26, 2013

Forty-six gene sequencing test for cancer patients in UK

Mar. 25, 2013 ? The first multi-gene DNA sequencing test that can help predict cancer patients' responses to treatment has been launched in the National Health Service (NHS), thanks to a partnership between scientists at the University of Oxford and Oxford University Hospitals NHS Trust.

The test uses the latest DNA sequencing techniques to detect mutations across 46 genes that may be driving cancer growth in patients with solid tumours. The presence of a mutation in a gene can potentially determine which treatment a patient should receive.

The researchers say the number of genes tested marks a step change in introducing next-generation DNA sequencing technology into the NHS, and heralds the arrival of genomic medicine with whole genome sequencing of patients just around the corner.

The many-gene sequencing test has been launched through the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), a collaboration between Oxford University Hospitals NHS Trust and Oxford University to accelerate healthcare innovation, and which has part-funded this initiative.

The BRC Molecular Diagnostics Centre carries out the test. The lab, based at Oxford University Hospitals, covers all cancer patients in the Thames Valley area. But the scientists are looking to scale this up into a truly national NHS service through the course of this year.

The new ?300 test could save significantly more in drug costs by getting patients on to the right treatments straightaway, reducing harm from side effects as well as the time lost before arriving at an effective treatment.

'We are the first to introduce a multi-gene diagnostic test for tumour profiling on the NHS using the latest DNA sequencing technology,' says Dr Jenny Taylor of the Wellcome Trust Centre for Human Genetics at Oxford University, who is programme director for Genomic Medicine at the NIHR Oxford BRC and was involved in the work. 'It's a significant step change in the way we do things. This new 46 gene test moves us away from conventional methods for sequencing of single genes, and marks a huge step towards more comprehensive genome sequencing in both infrastructure and in handling the data produced.'

Dr Anna Schuh, who heads the BRC Molecular Diagnostics Centre and is a consultant haematologist at Oxford University Hospitals, adds: 'Patients like the idea of a test that can predict and say up front whether they will respond to an otherwise toxic treatment. What the patient sees is no different from present. A biopsy is taken from the patient's tumour for genetic testing with a consultant talking through the results a few days later. It is part of the normal diagnostic process.'

Cancer is often described as a genetic disease, since the transition a cell goes through in becoming cancerous tends to be driven by changes to the cell's DNA. And increasingly, new cancer drugs depend on knowing whether a mutation in a single gene is present in a patient's cancer cells.

For example, a lung cancer patient may have a biopsy taken to check for changes in the EGFR gene. If there is a mutation, the patient may then be treated with a drug that works as an EGFR inhibitor. If there is no mutation, such drugs won't work and the patient would get a different drug that would be more effective for them. Knowing the presence or absence of mutations in a certain gene can choose the treatment path for that patient.

The NHS can currently test for mutations in 2 or 3 genes -- genes called BRAF, EGFR or KRAS -- using older sequencing technology that has been around for decades. Efforts are being made to look at increasing the number of cancer genes sequenced to nine as standard.

The Oxford scientists are the first to make such multi-gene tests possible in the NHS using the latest DNA sequencing techniques. The NHS service they have launched looks for mutations in 46 genes, and they are now working towards verifying the use of a test involving 150 genes.

Having a diagnostic test or 'panel' that can screen for mutations in multiple genes at once will be important for access to all the new cancer drugs that are coming along.

'It will be very difficult to manage in NHS diagnostic labs without gene panels,' explains Dr Schuh. 'Currently, new cancer drugs tend to get approved alongside a diagnostic test specific to that drug which can determine which patients will benefit. But as more and more drugs like this come along, we can't possibly run all the many different separate tests this could mean. We need one test for a range of drugs.'

Dr Taylor adds: 'We wanted a test that would use the latest DNA sequencing techniques to detect a wide range of mutations in a wide range of genes. A test that would be able to cover more cancers and more treatments, all for a similar cost to conventional methods.'

The test is run on a next generation sequencing platform from Life Technologies Corporation, called the Ion Personal Genome Machine (PGM(TM)). The test and accompanying software have been substantially modified as requested by the Oxford team to fulfil diagnostic standards in their lab.

This work was co-funded by the Technology Strategy Board, the UK's innovation agency, through a grant to the NIHR Oxford BRC, Life Technologies Corporation, AstraZeneca, and Janssen Research & Development, LLC, one of the Janssen Pharmaceutical Companies.

As part of the test development, the Oxford team looked to improve the initial sample preparation in the lab, and to provide the software and infrastructure support to handle and analyse the amount of information involved. Most importantly, the Oxford group has carried out tests and comparisons to verify the robustness of the technique with cancer biopsies direct from patients.

The team compared the new 46 gene test against conventional techniques for 80 consecutive cancer biopsies in the hospital lab's workflow.

The next-generation DNA sequencing method detected all the mutations the conventional method did; it detected new mutations the conventional method didn't; and detected mutations present at much lower levels in the samples. The time taken for the 46 gene test also fitted into the standard turnaround time for samples at the lab.

There is definite benefit in screening some of the 46 genes included in the test; there is probable or likely clinical benefit in screening some of the others; mutations in further genes might be important in some cancers but not others; and the other genes, we don't know as yet. But having this information means researchers can investigate whether a mutation has biological significance.

'We can keep data, bank it and link it with anonymised clinical data on patients' cancers for future research,' explains Dr Schuh.

The test looks for mutations in 'hotspot' regions of each gene -- areas where mutations are more likely to occur. This does mean the test may miss up to 5% of mutations, as they can occur elsewhere, but this is still significantly better than the 'false negative' rate using current methods.

It can also detect mutations present in only 5% of the tumour cells present in a sample. This is much lower than is possible currently, and is important in being able to capture information from cells present in only small numbers in a tumour, but which are still important in driving cancer growth.

Having shown that it is possible to introduce the 46 gene test as an NHS service, the researchers are now moving on to investigate the potential of a test that will sequence 150 genes. The team will use the test first of all with 500 existing samples from patients taking part in cancer clinical trials to be able to compare the results retrospectively with information from the trials. They will then use the test with 1000 new cancer biopsies to better understand how the extra information could be used in guiding treatments for patients and their outcomes.

Dr Schuh says: '"Panel" tests have significant potential while we wait for the cost of sequencing whole patient genomes to come down. Even then, panel tests may be with us for some time. After whole genome sequencing does come into use, it may be that panel tests are used first with patients' biopsies, with only those whose panel test shows no result having their entire DNA sequenced to look for rarer genetic changes.'

Lord Howe, Health Minister, said: 'We want to be among the best countries in the world at treating cancer and know that better tailored care for patients could potentially save lives.

'Health research like this is incredibly important and I'm delighted we could support the work of researchers in Oxford through the National Institute for Health Research Biomedical Research Centre.

'By rapidly translating findings from genetics research into real benefits for patients, their work will make sure that patients get the right treatments straight away, reduce potential side effects and also help us use NHS funds more effectively.'

The 46-gene panel is based on Ion AmpliSeq(TM) chemistry from Life Technologies Corporation. The test requires a very small amount of DNA (5 nanograms), an advantage when working with clinical samples that are typically limited in quantity.

The Ion Personal Genome Machine (PGM(TM) and Ion AmpliSeq(TM) are for Research Use Only, not intended for use in diagnostic procedures. Life Technologies intends to pursue CE-IVD designation for the PGM.

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Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/auuouxKLTHo/130325101533.htm

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Cyprus central bank to impose capital controls

NICOSIA, Cyprus (AP) ? Cyprus' president says the central bank will impose some limits on bank transactions on Tuesday, when most of the country's financial institutions reopen for the first time in over a week.

All banks except the Bank of Cyprus and Laiki are due to reopen on Tuesday morning. President Nicos Anastasiades did not specify what limitations would be imposed on transactions.

He said it was a "very temporary measure, which will gradually be relaxed."

The country's banks have been closed while politicians set up a plan to secure funding for an international bailout, after lawmakers rejected an initial scheme that would have seized up to 10 percent of people's accounts.

A deal securing the bailout was reached early Monday.

Source: http://news.yahoo.com/cyprus-central-bank-impose-capital-controls-192502277--finance.html

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Monday, March 25, 2013

AP sources: SD Sen. Johnson won't seek re-election (The Arizona Republic)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, News Feeds and News via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/294522214?client_source=feed&format=rss

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Sandusky speaks again, maintains innocence

FILE - In this Oct. 9, 2012 file photo, former Penn State University assistant football coach Jerry Sandusky leaves the Centre County Courthouse after being sentenced in Bellefonte, Pa. An interview with Sandusky is expected to be aired on NBC's ?Today? show Monday March 25, 2013, a rare instance of the former Penn State assistant football coach giving his own side of the story. (AP Photo/Gene J. Puskar, File)

FILE - In this Oct. 9, 2012 file photo, former Penn State University assistant football coach Jerry Sandusky leaves the Centre County Courthouse after being sentenced in Bellefonte, Pa. An interview with Sandusky is expected to be aired on NBC's ?Today? show Monday March 25, 2013, a rare instance of the former Penn State assistant football coach giving his own side of the story. (AP Photo/Gene J. Puskar, File)

(AP) ? Nine months after being convicted of sexually abusing 10 boys ? a scandal that destroyed the once unimpeachable reputation of Hall of Fame coach Joe Paterno ? Jerry Sandusky is again claiming he did nothing wrong.

Sandusky has rarely spoken about the allegations, although he has consistently maintained his innocence since his November 2011 arrest. The latest statements came Monday in portions of a taped interview aired on NBC's "Today" and transcripts posted on the web site of a filmmaker who aims to clear Paterno's name.

In the interviews, the former Penn State assistant coach denied having inappropriate contact with the boys, although he acknowledged he may have "tested boundaries."

"Yeah, I hugged them," Sandusky said, according to transcripts posted on the filmmaker's site. "Maybe I tested boundaries. Maybe I shouldn't have showered with them. Yeah, I tickled them.

"I looked at them as being probably younger than even some of them were. But I didn't do any of these horrible acts and abuse these young people. I didn't violate them. I didn't harm them."

Although Sandusky's comments aired and posted Monday were given to a man endeavoring to clear Paterno's name, the late coach's family has distanced themselves from the statements.

Wick Sollers, a Paterno family lawyer, said in a statement that Sandusky's statements are "transparently self-serving and yet another insult to the victims."

"The Paterno family would prefer to remain silent on this matter, but they feel it is important to make it clear that they had no role in obtaining or releasing this recording," Sollers said. "Moreover, they believe that any attempt to use this recording as a defense of Joe Paterno is misguided and inappropriate."

Sandusky told filmmaker John Ziegler he was not sure whether Paterno, who was fired after Sandusky's arrest, would have let him keep coaching if he suspected Sandusky was a pedophile. Sandusky was investigated by university police after showering with a boy on campus in 1998, but remained one of Paterno's top assistants through 1999.

"If he absolutely thought I was, I'd say no," Sandusky said in the audio recording. "If he had a suspicion, I don't know the answer to that."

Not long after his arrest, Sandusky also denied wrongdoing in an interview on NBC's "Rock Center." In halting statements, he acknowledged showering with young boys and engaging in what he called "horseplay."

On the eve of his sentencing in October, Sandusky told a Penn State radio station he was the victim of a "well-orchestrated effort" by his accusers, the media, Penn State, plaintiffs' attorneys and others.

"I speak today with hope in my heart for a brighter day, not knowing if that day will come," Sandusky said in October. "Many moments have been spent looking for a purpose. Maybe it will help others, some vulnerable children who might have been abused, might not be, as a result of the publicity."

Ziegler said the interviews were conducted during three sessions, and told the AP on Monday that additional excerpts will be posted online over the coming days. The transcripts were posted by Ziegler on his site, www.framingpaterno.com.

He describes himself as an author, broadcaster, commentator and maker of films, including the 2009 movie, "Media Malpractice: How Obama Got Elected and Palin Was Targeted."

Along with the Sandusky interview material, Ziegler posted a piece about himself that anticipates critical media coverage of his background. As an example, he noted he has been "fired in radio lots of times for saying things which seem outrageous."

Penn State, which funded an investigation by former FBI director Louis Freeh that concluded Paterno and other top university officials covered up allegations against Sandusky in order to protect the school's reputation, issued a statement that said Sandusky's latest remarks "continue to open wounds for his victims, and the victims of child sexual abuse everywhere."

Attorneys for a young man who says he is "Victim 2" ? the boy whose assault in a team shower in 2001 was witnessed by then graduate assistant Mike McQueary ? said Sandusky's victims "have heard enough from Jerry Sandusky."

The lawyers ? Joel Feller, Matt Casey, Justine Andronici and Andrew Shubin ? issued a statement Monday saying Victim 2 and their other clients are focusing on "healing and holding Penn State accountable for choosing to protect Jerry Sandusky and themselves instead of protecting children from years of horrific sexual abuse."

Sandusky, 69, is serving a 30- to 60-year prison sentence after being convicted last year of 45 counts of child sexual abuse. He is pursuing appeals.

___

Scolforo reported from Harrisburg, Pa.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-03-25-Penn%20State-Abuse/id-f3e8153944104c71867c0ddd819ebc2f

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Toenail clippings to measure toxic exposure in NJ

GARFIELD, N.J. (AP) -- The neighborhood looks exceedingly normal: single-family homes and apartment buildings packed together, dogs barking from postage-stamp-size lawns, parents hustling down narrow sidewalks to fetch their children from school. But something with very dangerous potential lies below the surface, officials say.

The residents' toenails will provide confirmation.

A plume of hexavalent chromium, a metal used in industrial production that the Centers for Disease Control and Prevention calls a "well-established carcinogen," has spread under Garfield, putting about one-tenth of the city's homes ? about 600 structures and 3,600 residents ? at risk.

The Environmental Protection Agency is about to start drilling on the spill site to determine how much chromium is pooled beneath and remove tainted soil. The agency is also testing the broader area to determine how it will be cleaned up. Now a group of scientists from New York University is working to assess how much chromium residents may have been exposed to.

Researchers will collect toenail clippings from city residents. The nails will be tested for traces of chromium. Because toenails grow slowly, it is possible to see how much chromium has accumulated in the body over the past 18 months or so, said Judith Zelikoff, a professor of environmental medicine at New York University.

"Our major goal is to try to relieve their fears," Zelikoff said. "With the economy, they can't sell their homes. They don't know if they got exposed."

The contamination started 30 years ago, when thousands of pounds of hexavalent chromium? the same stuff that sickened Californians whose story was told in "Erin Brockovich" ? leaked from a tank at the EC Electroplating Co., a factory surrounded on all sides by houses and apartments. The state started cleaning up the spill but stopped two years later. In 1993, chromium was found at a now-shuttered firehouse and later in homes.

The EPA designated the area as a Superfund site ? marking it as of the nation's most toxic uncontrolled hazardous waste sites ? in 2011, and officials cautioned residents to stay out of their basements to prevent potential chromium exposure. EPA officials removed chromium from the building and demolished it last year, and found that some tanks had holes in them, potentially releasing even more chromium into the groundwater.

Officials say the contamination has not affected the city's drinking water, which is drawn from an outside source. Instead, they worry that people could inhale chromium dust that has been found in basements where groundwater has leached in.

The chromium plume is about three-quarters of a mile wide and slightly more than an eighth-mile long, EPA officials said. The substance has traveled from the site underneath the Passaic River and into the city of Passaic. The agency has installed about 40 monitoring wells to monitor how far the metal has spread.

"We're trying to find out the extent of the plume," said Rich Puvogel, a project manager with the EPA.

High quantities of the metal have been found in 14 homes that have since been cleaned up. Trace amounts were found in 30 to 40 homes. Testing continues, and a nearby school did not show elevated chromium levels.

Cathy Garrone, who bought a house in the neighborhood in 1985, walked her small dog recently across the street from the site where the plant once stood, a lot now fenced off and peppered with mounds of rocks and dirt.

She said she wouldn't have bought there if she had known about the chromium spill, and thinks much more testing needs to be conducted, both of the environment and people.

"I'd like them to do more testing to assure my safety," she said.

The research study is being done in conjunction with the city of Garfield. Officials are hoping the testing can bring some answers to residents.

"It's just been left," Zelikoff said. "A lot of people made mistakes."

Zelikoff and her team hope to test as many as 250 residents; some must live close to the plume and others about 3 miles away as a control group. When residents sign up, they will be given a kit that contains stainless steel toenail clippers (cheap ones contain chrome), instructions on how to clip the nails (samples from all 10 are needed) and an envelope for the clippings. It will take weeks to know the results, and people will be advised by public health nurses and others once the results return.

Test subjects must be between 18 and 65, have lived in Garfield for at least two years, not take chromium supplements, and not smoke.

Many residents are immigrants and relative newcomers, and some don't know about the contamination, Zelikoff said. City officials are working to educate residents, disseminating information about the cleanup to local churches and in four languages: English, Spanish, Polish and Macedonian, said city manager Tom Dutch.

Dutch said an initial health consultation indicates that there's no higher incidence of cancer in the neighborhood than anywhere else in the city, but he thinks the issue needs additional scientific testing.

"I have some concerns," Dutch said. "There are residents who have come to meetings and said, 'This one died, that one died,' and I think it warrants further investigation."

___

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Source: http://news.yahoo.com/toenail-clippings-measure-toxic-exposure-142640404.html

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Northern Irish police defuse car bomb near G8 venue

BELFAST (Reuters) - Northern Irish police defused a bomb in a car on Saturday close to where G8 leaders will meet at a summit in June and said that the device was likely to have been intended for a police station nearby.

Army bomb disposal experts defused the device after a security operation that lasted almost 36 hours in the county Fermanagh town of Enniskillen. The Group of Eight leaders meet just outside the town in three months' time.

A senior Northern Irish officer said police believed the bomb was en route to a police station in a town nearby and would have killed or injured people if it had not been intercepted.

"Once again our community has been disrupted and the lives of residents put at risk by an element intent on causing loss of life and disruption," District Commander Pauline Shields said in a statement.

"The people responsible for this have no regard for the lives of anyone in our community. It is fortunate that no-one was killed or seriously injured as a result of this reckless act."

A 1998 peace deal largely ended more than three decades of violence in the British-controlled province between mainly Catholic Irish nationalists seeking union with Ireland and predominantly Protestant unionists who want to remain part of the United Kingdom.

However militant nationalists, who include former operatives who split from the Irish Republican Army (IRA) after it declared a ceasefire, still stage sporadic gun and bomb attacks and have targeted security forces in particular.

An attempt to fire mortar bombs at a police station was foiled earlier this month in what would have been the first attack of its kind in the United Kingdom since the peace deal ended the IRA's campaign of violence.

(Reporting by Ian Graham; Editing by Padraic Halpin and Michael Roddy)

Source: http://news.yahoo.com/northern-irish-police-defuse-car-bomb-near-g8-140147653.html

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Sunday, March 24, 2013

Genetic analysis saves major apple-producing region of Washington state

Mar. 22, 2013 ? In August 2011, researchers from the U.S. Department of Agriculture were presented with a serious, and potentially very costly, puzzle in Kennewick, Wash. Since Kennewick lies within a region near the heart of Washington state's $1.5 billion apple-growing region, an annual survey of fruit trees is performed by the Washington State Department of Agriculture (WSDA) to look for any invading insects. This time the surveyors discovered a crabapple tree that had been infested by a fruit fly that they couldn't identify.

It was possible that the fly's larvae, eating away inside the crabapples as they grew toward adulthood, belonged to a relatively harmless species that had simply expanded its traditional diet. In that case, they posed little threat to the surrounding apple orchards in central Washington.

But the real fear was that they represented an expansion in the range of the invasive apple maggot fly, known to biologists as Rhagoletis pomonella. If so, then this would trigger a costly quarantine process affecting three counties in the state.

"In one of the world's leading apple-growing regions, a great deal of produce and economic livelihood rested on quickly and accurately figuring out which one of the flies was in that tree," says Jeffrey Feder, professor of biological sciences and a member of the Advanced Diagnostics & Therapeutics initiative (AD&T) at the University of Notre Dame. "And for these flies, it can sometime turn out to be a difficult thing to do."

As Feder and his team, including graduate student Gilbert St. Jean and AD&T research assistant professor Scott Egan, discuss in a new study in the Journal of Economic Entomology, the WSDA sent larvae samples to Wee Yee, research entomologist at the USDA's Yakima Agricultural Research Laboratory in Wapato, Wash. One larva was sent to Notre Dame for genetic analysis. The study sought to compare Notre Dame's genetic analysis to Yee's visual identification after the larvae had developed into adults. Fortunately, the fly identified, Rhagoletis indifferens, is not known to infest apples. The Notre Dame group further demonstrated that it is possible to genetically identify the correct fly species within two days, compared to the four months required to raise and visually identify the fly.

A separate study led by the Feder lab details how the apple maggot fly was recently introduced into the Pacific Northwest region of the U.S., likely via larval-infested apples from the East. The flies have subsequently reached as far north as British Columbia, Canada, and as far south as northern California. So far, though, the apple maggot has not been reported infesting any commercial apple orchards in central Washington.

"The correct identification of the larvae infesting crabapple trees saved the local, state and federal agencies thousands of dollars in monitoring, inspection and control costs," Yee said. "The cost to growers if the apple maggot had been found to be established in the region would have been very substantial (easily over half a million dollars), but the rapid diagnostic test developed at Notre Dame suspended the need to proceed with the rulemaking process, saving staff and administrative costs."

The Feder team is continuing to refine the genetic assays to develop a portable test that would be valuable in apple-growing regions, as well as ports of entry where fruit infested by nonlocal insect species can be rapidly detected, to prevent the spread of the insect.

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The above story is reprinted from materials provided by University of Notre Dame. The original article was written by Kirk Reinbold.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/EdUmIXVehyk/130323152914.htm

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Report: Dell likely to receive more takeover bids

Michael Dell may face some competition in his effort to take over the computer maker he founded.

The Wall Street Journal reported on its web site Saturday that buyout specialist Blackstone Group and activist investor Carl Icahn have both notified a special committee of Dell Inc.'s board that they are working on bids for the company.

Michael Dell and a group of investors announced their bid, valued at $24.4 billion, in early February. The Round Rock, Texas, company's board then set a 45-day period to allow for offers that might top that bid. That period expired Friday.

The Journal, citing unnamed sources, reported that the notification will allow Blackstone and Icahn four more days to develop their offers.

A Dell representative declined comment on the report. Blackstone and Icahn representatives did not immediately return calls from The Associated Press seeking comment.

Icahn and other investors have criticized the $13.65 a share offer from the Michael Dell group as being too low. Several buyout scenarios tying Blackstone to Dell have been leaked to the media this week. Dell shares closed Friday at $14.14, an indication that investors expected to see a higher bid. Some analysts have predicted Dell ultimately will be sold for $15 to $16 per share.

Southeastern Asset Management, Dell's second largest shareholder after Michael Dell, has asserted the company is worth closer to $24 per share.

For its part, the four-member board committee maintains it's selling Dell at a fair price, one that reflects the dimming prospects for the PC industry as more technology spending shifts to smartphones and tablet computers.

Dell, the world's third-largest PC maker, has said Friday's deadline for competing offers could be extended if its board believes other suitors would benefit from more time to examine Dell's books and hash out other details.

The company has promised to provide extensive details about the sales process in regulatory documents that are supposed to be filed next week.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-03-23-Dell-Acquisition/id-e1ae6f7a2bb84748bf4c33e0f727bd2f

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Saturday, March 23, 2013

Lebanese state news agency says PM to resign

BEIRUT (AP) ? Lebanon's state news agency says Prime Minister Najib Mikati will announce his resignation.

The National News Agency said late Friday that Mikati would soon give a speech announcing his decision, but gave no further details.

Lebanese media have speculated that Mikati would quit his post due to a parliamentary impasse over the extension of the tenure of Lebanon's police chief, Maj. Gen. Ashraf Rifi.

Shiite militant group Hezbollah, which dominates the parliament, considers Rifi a foe and has said it won't support the extension.

Mikati's resignation would need to be accepted by President Michel Suleiman before it becomes official.

Source: http://news.yahoo.com/lebanese-state-news-agency-says-pm-resign-185318701.html

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Chinua Achebe The Writer Lives On ? Africa is a Country


By Mukoma Wa Ngugi

?Sir, I am very happy to finally meet you in person ? I have read all your books,? a man gushed to my father, Ngugi Wa Thiong?o at the Jomo Kenyatta Airport, Nairobi. My father loves talking with people, but he also does not mind a compliment or two and so we stopped to chat. ?Your books, especially Things Fall Apart???

And on another occasion my friends and I were sitting in a bar in Madison Wisconsin when a drunken student stumbled to our table. ?I hear you are the son of that famous African writer?? He asked me.

?Yes, I happen to be,? I replied and sat up straight to cheerfully receive a few proxy compliments.

?We just finished reading Things Fall Apart in class ? now that Okonkwo character??

Suffice it to say then that Chinua Achebe has been around all my life ? from the Heinemann Series poster of a smiling, serious, bemused, pipe smoking Achebe that was framed in our family sitting room, to cases of mistaken identity, to my own work as a writer and teacher.

In fact just last month, I was teaching Things Fall Apart alongside Joseph Conrad?s Heart of Darkness. The question at hand was ? how does Achebe counter and answer Conrad?s Africa? One word comes to mind ? voice. To my ear Achebe?s voice is always measured even at its most defiant.

It?s a voice strong enough to speak for a continent denied its voice by colonial racism. It?s the voice of a humble listener who is moved into action by what he sees and hears around him. There Was A Country is as much about Biafra as it is about how Achebe answered the question ? what is the role of the African writer in a decolonizing Africa? Jump into your times with both your feet and pen.

Thinking about the African literary tradition and the humility to listen, Achebe never accepted the title, ?father of African literature? that we are now forcefully bestowing on him. When asked about it in 2009, he told the Brown Daily Herald that he ?strongly resisted? the title because ?it?s really a serious belief of mine that it?s risky for anyone to lay claim to something as huge and important as African literature ? the contribution made down the ages. I don?t want to be singled out as the one behind it because there were many of us ? many, many of us.?

With Achebe, Nelson Mandela and others who have challenged the way we live and think about the world, there will be areas of disagreements. So with Achebe there are questions around his stand on the role of African languages in African writing. Things Fall Apart has been translated into 50 languages ? how many of them are African languages? How many of the translations are in a Nigerian language? There is also much to be argued about in regards to his representation of the Biafra war and Ibo nationalism in There was a Country.

But there is a counter-argument to be made that the work of my generation of African writers is to shine a light on his blind spots. We can give Things Fall Apart new lives in African languages. And we should tell our histories in as many different ways as we can so that there are multiple mirrors reflecting our tragedies and triumphs.

The bottom line for me is this ??We are all better off because he lived and beautifully wrote his conscience. A writer who has left so much of himself in the world and on whose shoulders others will stand for generations to come cannot be said to be truly dead.

Achebe the man has died. Achebe the writer lives on.

*?Mukoma Wa Ngugi is an Assistant Professor of English at Cornell University, the author of Nairobi Heat (Melville, 2011) and the forthcoming Black Star Nairobi (Melville, 2013).

Source: http://africasacountry.com/2013/03/22/chinua-achebe-the-writer-lives-on/

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The cash register rings its last sale

In this Friday, Feb. 15, 2013, photo, a sales staff member at Barney's New York uses an iPod Touch to help a customer make a purchase, in New York. Stores across the country are ditching the old-fashioned, clunky cash registers and instead having salespeople _ and shoppers themselves _ checkout on smartphones and tablet computers. (AP Photo/Bebeto Matthews)

In this Friday, Feb. 15, 2013, photo, a sales staff member at Barney's New York uses an iPod Touch to help a customer make a purchase, in New York. Stores across the country are ditching the old-fashioned, clunky cash registers and instead having salespeople _ and shoppers themselves _ checkout on smartphones and tablet computers. (AP Photo/Bebeto Matthews)

In this Friday, Feb. 15, 2013, photo, a sales staff member at Barney's New York uses an iPod Touch to help a customer make a purchase, in New York. Stores across the country are ditching the old-fashioned, clunky cash registers and instead having salespeople _ and shoppers themselves _ checkout on smartphones and tablet computers. (AP Photo/Bebeto Matthews)

In this Friday, Feb. 15, 2013, photo, a sales staff member at Barney's New York uses an iPod Touch to help a customer make a purchase, in New York. Stores across the country are ditching the old-fashioned, clunky cash registers and instead having salespeople _ and shoppers themselves _ checkout on smartphones and tablet computers. (AP Photo/Bebeto Matthews)

(AP) ? Ka-ching! The cash register may be on its final sale.

Stores across the country are ditching the old-fashioned, clunky machines and having salespeople ? and even shoppers themselves ? ring up sales on smartphones and tablet computers.

Barneys New York, a luxury retailer, this year plans to use iPads or iPod Touch devices for credit and debit card purchases in seven of its nearly two dozen regular-price stores. Urban Outfitters, a teen clothing chain, ordered its last traditional register last fall and plans to go completely mobile one day. And Wal-Mart, the world's largest retailer, is testing a "Scan & Go" app that lets customers scan their items as they shop.

"The traditional cash register is heading toward obsolescence," said Danielle Vitale, chief operating officer of Barneys New York.

That the cash register is getting the boot is no surprise. The writing has been on the wall for a long time for the iconic machine, which was created in the late 1800s. The register was essential in nearly every retail location by 1915, but it now seems outdated in a world in which smartphones and tablets increasingly are replacing everything from books to ATMs to cameras.

Stores like smartphones and tablets because they take up less floor space than registers and free up cashiers to help customers instead of being tethered to one spot. They also are cheaper: For instance, Apple Inc.'s iPads with accessories like credit card readers can cost a store $1,500, compared with $4,000 for a register. And Americans increasingly want the same speedy service in physical stores that they get from shopping online.

"Consumers want the retailer to bring the register to them," said Lori Schafer, executive adviser at SAS Institute Inc., which creates software for major retailers.

J.C. Penney, a mid-price department-store chain, said the response by customers has been great since it started rolling out iPod Touch devices late last year in its 1,100 stores. The goal is to have one in the hands of every salesperson by May. The company said that about a quarter of purchases at its stores nationwide now come from an iPod Touch.

On a recent Thursday afternoon at a Penney store in the Manhattan borough of New York City, Debbie Guastella, 55, marveled after a saleswoman rang up three shirts she was buying on an iPod Touch.

"I think it's great," said Guastella, who lives in Huntington, N.Y. "The faster the better."

It's been a long fall for the cash register, which innovated retail as we know it. The first register was invented following the Civil War by a little known saloon owner. Before then, most store owners were in the dark about whether or not they were making a profit, and many suffered since it was easy for sales clerks to steal from the cash drawer unnoticed. But by 1915, cash registers were ubiquitous in stores across the country, with more than 1.5 million sold by then.

More recently, stores have been looking for ways to modernize checkout. Since 2003, self-checkout areas that enable customers to scan and bag their own merchandise have become commonplace in grocery and other stores. But recently, there's been a push to go further.

As a result, companies that make traditional cash registers are racing to come up new solutions. NCR Corp., formerly known as the National Cash Register Co., was the first to manufacturer the cash register on a large scale.

Last year, the company that also makes ATMS, self-service checkout machines and airport check-in kiosks, launched a program that merges its software with the iPad. This allows store clerks to detach the iPad from the keyboard at the counter and use it as a mobile checkout device

"Retailers have more flexibility and more opportunities to change the shopping experience," said Mark Self, NCR's vice president of retail solutions marketing.

Stores themselves are also taking their cues from the success of Apple Inc. The nation's most profitable retailer moved to mobile checkout in its stores in 2006.

Take upscale handbag maker Coach, which is using iPod Touch devices at half of its 189 factory outlet stores. The company also is testing them in a handful of its 350 regular stores.

The move has enabled Coach to start slimming down its registers to the size of small podiums, leaving extra space that is equivalent to three days of product and a display table for the average store, said Francine Della Badia, Coach's executive vice president of merchandising.

Badia, who says the additional space will be used for new shoe salons and other purposes, said most importantly, the mobile devices allow store staff to build "a more intimate connection with the customer."

Some retailers have decided to go completely mobile. Urban Outfitters, which operates more than 400 stores under its namesake brand, Anthropologie and Free People, announced in late September that all sales eventually will be rung up on iPods and iPads on swivels located at counters. The company didn't give a timeframe for when it would go completely mobile.

Urban Outfitters had given iPod Touch devices to its sales staff two years ago and the move has been very well received by shoppers, said Calvin Hollinger, the company's chief information officer in his address to investors.

Nordstrom, an upscale department-store chain that's considered within the retail industry to be the gold standard in customer service, also plans to get rid of registers altogether.

The company handed out iPod Touch devices to its staff at its 117 department stores nationwide in 2011. And by late last year, it did the same for its 110 Nordstrom Rack stores that sell lower-priced merchandise. Nordstrom, which already has removed some of the registers at its Rack stores, said it aims to phase out registers by next year.

Colin Johnson, a Nordstrom spokeswoman, said it's too early to draw any conclusions on how mobile checkout has influenced buying, but the company is learning about which technologies work best.

"We see the future as essentially mobile," Johnson said. "We don't see departments in our store as being defined by a big clunky cash register."

Not every retailer is quick to ditch registers, though. After all, there are still logistics to figure out. For instance, no retailer yet is accepting cash payments on mobile devices. But if they start to do so, where will they put the cash that would normally go into a register?

Additionally, sales staff walking around stores armed with mobile devices could turn off shoppers who would prefer to be left alone in aisles. To remedy that, some retailers are training their salespeople on when to approach shoppers ? and when not to.

For its part, Wal-Mart is putting checkout in the hands of the shoppers themselves.

The retailer is testing its "Scan & Go" app, which can be used on Apple devices such as iPads, in more than 200 of its more than 4,000 stores nationwide.

The app, which is aimed at reducing long checkout lines, requires that shoppers pay at self-checkout areas. So as it tests the app, Wal-Mart also is expanding the number of self-checkout areas in its stores.

"Our goal is to give choices to all of our customers however they want to shop," said Gibu Thomas, senior vice president of mobile and digital initiatives at Wal-Mart's global e-commerce division."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-03-22-Death%20of%20Cash%20Register/id-1d047ea6ecff46aa9435165bff364a43

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Friday, March 22, 2013

Men and women get sick in different ways: Developing gender-specific medicine is a major challenge of the future

Mar. 22, 2013 ? Recent research in laboratory medicine has revealed crucial differences between men and women with regard to cardiovascular illness, cancer, liver disease, osteoporosis, and in the area of pharmacology.

At the dawn of the third millennium medical researchers still know very little about gender-specific differences in illness, particularly when it comes to disease symptoms, influencing social and psychological factors, and the ramifications of these differences for treatment and prevention. Medical research conducted over the past 40 years has focused almost exclusively on male patients.

A new article titled "Gender medicine: a task for the third millennium" presents research on gender-related differences conducted by Giovannella Baggio of Padua University Hospital and her team.

The article, which appears in the journal Clinical Chemistry and Laboratory Medicine (CCLM), highlights evidence for considerable differences between the sexes in five domains -- cardiovascular disease, cancer, liver diseases, osteoporosis, and pharmacology.

Typically perceived as a male illness, cardiovascular disease often displays markedly different symptoms among women. While a constricted chest and pain that radiates through the left arm are standard signs of heart attack in men, in women the usual symptoms are nausea and lower abdominal pain. Although heart attacks in women are more severe and complicated, when complaining of these non-specific symptoms women often do not receive the necessary examination procedures, such as an ECG , enzyme diagnostic tests or coronary angiography.

Colon cancer is the second most common form of cancer among men and women. However, women suffer this illness at a later stage in life. Furthermore, colon tumors typically have a different location in women, and they respond better to specific chemical treatments. Gender also has an impact on the patient's responsiveness to chemotherapy administered to treat cancer, such as colon, lung, or skin cancer. In this way, gender impacts the course of the disease and the patient's chances for survival.

Primary biliary cirrhosis is a liver disease that primarily affects women. The authors of the study provide clear evidence that for this disease and chronic hepatitis C, the genetic makeup and differing hormone levels of females are a primary risk factor. This finding also applies to osteoporosis. While typically viewed as a female disease because of the much higher rate of female patients, osteoporosis also strikes men. The study contends that osteoporosis is too often overlooked in male patients, and it documents a higher mortality rate among men suffering bone fractures.

Baggio and her team also show variation between men and women in the pharmacology of aspirin and other substances. Differences in action and side effects are attributable to different body types, varying reaction times in the absorption and elimination of substances, and a fundamentally different hormonal status. Thus, to administer medication safely and effectively, the dosage and duration of treatment must take the patient's gender into account.

The study concludes that additional and more far-reaching clinical investigations of gender differences are needed in order to eliminate fundamental inequalities between men and women in the treatment of disease.

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Journal Reference:

  1. Giovannella Baggio, Alberto Corsini, Annarosa Floreani, Sandro Giannini, Vittorina Zagonel. Gender medicine: a task for the third millennium. Clinical Chemistry and Laboratory Medicine, 2013; 0 (0): 1 DOI: 10.1515/cclm-2012-0849

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/ZvFzAurIc-I/130322090850.htm

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Man plans fake attack in hopes of impressing woman (bad idea)

File photo of police lights (Thinkstock)File photo of police lights (Thinkstock)

How to impress a woman? The question has befuddled generations of men. Sure, you could go the traditional route and offer a few thoughtful compliments while subtly mentioning that you were all-county shot-put in high school. Or, you could do what a Jonesboro, Ark., man did and stage a knife attack in a parking lot.

Not surprisingly, Jeffrey Tyler Siegel's ruse didn't go quite as planned. According to KAIT-8, Siegel and a woman he was out on a date with were walking after an evening out. That's when a man in black appeared and told Siegel, "You can go. But your girlfriend stays."

Siegel's date screamed and ran off to get help, while Siegel claimed he stayed and fought the knife-wielding attacker. Police and canine units searched the surrounding area for the attacker but came up empty. After a few hours, the hunt was called off.

Investigators contacted the woman about the attack a few days later and she said something interesting: Siegel had been texting a lot and acting odd in the minutes leading up it.

Cops brought the hapless Casanova in for questioning. After they assured him that they wouldn't press charges if he came clean, he spilled the beans. He'd set up the entire thing as a way to impress his lady friend. The "attacker" was a friend and everything had been staged.

KAIT-8 reports that, according to the police report, Siegel said, "He did not ever intend on it going this far and that he did not plan on the police being notified. He said it just really got out of hand very fast."

The station spoke with the man's date, who commented that the fake attack didn't have the effect Siegel had hoped it might. It "was not very heroic," she said.

Source: http://news.yahoo.com/blogs/sideshow/man-plans-fake-attack-hopes-impressing-woman-bad-153026262.html

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